List of publications - Achim Paululat

Bold: Authors from the Lab


  1.     Lammers, K., Abeln, B., Hüsken, M., Lehmacher, C., Psathaki, O.E., Alcorta, E., Meyer, H. and Paululat, A. (2017) Formation and function of intracardiac valve cells in the Drosophila heart. Journal of Experimental Biology (JEB) 220 (10): 1852-1863.

  2.     Sellin, J., Schulze, H., Paradis, M., Gosejacob, D., Papan, C., Shevchenko, A., Psathaki, O.E., Paululat, A., Thielisch, M., Sandhoff, K. and Hoch, M. (2017) Characterization of Drosophila saposin-related mutants as a model for lysosomal shingolipid storage diseases. Disease Models & Mechanisms (DMM) 10 (6): 737-750.

  3.     Thiel, D., Hugenschütt, M., Meyer, H., Paululat, A., Quijada-Rodriguez, A., Purschke, G. and Weihrauch, D. (2017) Ammonia excretion in the marine polychaete Eurythoe complanata (Annelida) Journal of Experimental Biology 220: 425-436.

  4.     Hallier, B., Schiemann, R., Cordes, E., Vitos-Faleato, J., Walter, S., Heinisch, J.J., Malmendahl, A., Paululat, A. and Meyer, H. (2016) Neprilysins control insulin signaling via cleavage of regulatory peptides. eLIFE 2016,5:e19430

  5.     Rotstein, B. and Paululat A. (2016) On the morphology of the Drosophila heart. Journal of Cardiovascular Development and Disease (JCDD) 3, 15: 1-13.

  6.     Ivy, J.R., Drechsler, M., Catterson, J.H., Bodmer, R., Ocorr, K., Paululat, A. and Hartley, P. (2015) Klf15 is critical for the development and differentiation of Drosophila nephrocytes. PLoS One 10(8): e134620.

  7.     Pass, G., Tögel, M., Krenn, H. and Paululat, A. (2015) The circulatory organs of insect wings: prime examples for the origin of evolutionary novelties. Zoologischer Anzeiger 256: 82-95.

  8.     Hallier, B., Hoffmann, J., Roeder, T., Tögel, M., Meyer, H. and Paululat, A. (2015) The bHLH transcription factor Hand regulates the expression of genes critical to heart and muscle function in Drosophila melanogaster. PLoS One 10(8): e0134204.

  9.     Bohnekamp, J., Cryderman, D.E., Paululat, A., Baccam, G., Wallrath, L.L. and Magin, T.M. (2015) A Drosophila model of Epidermolysis Bullosa Simplex. Journal of Investigative Dermatology (JID) 135(8): 20131-2039

  10.     Hüsken, M., Hufnagel, K., Mende, K., Appel, E, Meyer, H., Peisker, H, Tögel, M., Wang, S., Wolff, J., Gorb, S.N. and Paululat, A. (2015) Adhesive pad differentiation in Drosophila melanogaster depends on the Polycomb group gene Su(z)2. Journal of Experimental Biology 218: 1159-1165

  11.     Heinisch, J. & Paululat, A. (Eds. of the german edition) (2015) Campbell Biologie. 10. German Edition. Authors: Reece, Urry, Cain, Wassermann, Minorsky, Jackson Campbell Biology. Pearson Deutschland GmbH. ISBN 386894259

  12.     Volk, T., Wang, S., Rotstein, B. and Paululat, A. (2014) Matricellular proteins in development: Perspectives from the Drosophila heart. Matrix Biology 37C: 162-166

  13.     Moschner, K., Sündermann, F., Meyer, H., da Graca, A.P., Appel, N., Paululat, A., Bakota, L. and Brandt, R. (2014) RNA-protein granules modulate tau isoform expression and induce neuronal sprouting. Journal of Biological Chemistry 289 (24): 16814-16825

  14.     Rosemeyer, H., Paululat, A. and Heinisch, J.J. (2014) „Yeast mail“: A novel Saccharomyces application (NSA) to encrypt messages. Chemistry & Biodiversity 11(9): 1364-1373

  15.     Drechsler, M., Schmidt, A., Meyer, H. and Paululat, A. (2013) The conserved ADAMTS-like protein Lonely heart mediates matrix formation and cardiac tissue integrity. PLOS Genetics 9(7): e1003616

  16.     Tögel, M., Meyer, H., Heinisch, J.J., Lehmacher, C., Pass, G. and Paululat, A. (2013) The bHLH transcription factor Hand is required for proper wing heart formation in Drosophila. Developmental Biology 381(2): 446-459

  17.     Tögel, M., Pass, G. and Paululat, A. (2013) In vivo imaging of Drosophila wing heart development during pupal stages. International Journal of Developmental Biology 57: 13-24

  18.     Brandt, R. and Paululat, A. (2013) Microcompartments in the Drosophila heart and the mammalian brain: general features and common principles. Biological Chemistry 394(2): 217-230

  19.     Paululat, A. and Heinisch, J.J.H. (2012) New Yeast/E.coli/Drosophila triple shuttle vectors for efficient generation of Drosophila P-element transformation constructs. Gene 511(2): 300-305

  20.     Lehmacher, C., Abeln, B. and Paululat, A. (2012) The ultrastructure of Drosophila heart cells. Arthropod Structure and Development 41: 459-474

  21.     Panz, M. , Vitos-Faleato, J.V., Jendretzki, A., Heinisch, J., Paululat, A. and Meyer, H. (2012) A novel role for the non catalytic intracellular domain of Neprilysins in muscle physiology. Biology of the Cell 104: 1-16

  22.     Wang, S., Meyer, H., Ochoa-Espinosa, A., Buchwald, U., Önel, S., Altenhein, B., Heinisch, J., Affolter, M. and Paululat, A. (2012) GBF1 (Gartenzwerg)-dependent secretion is required for Drosophila tubulogenesis. Journal of Cell Science 125: 461-472

  23.     Albrecht, S., Altenhein, B., Paululat, A. (2011) The transmembrane receptor Unc5 is essential for cardiac tube alignment and lumen formation in Drosophila. Developmental Biology 350: 89-100

  24.     Meyer, H., Panz, M., Albrecht, S., Drechsler, M., Wang, S., Hüsken, M., Lehmacher, C. and Paululat, A. (2011) Drosophila metalloproteases in development and differentiation: The role of ADAM proteins and their relatives. European Journal of Cell Biology 90 (9): 770-778

  25.     Paululat, A. & Purschke, G. (2011) Wörterbuch der Zoologie. 519 pages, Spektrum Akademischer Verlag, Heidelberg. 8. Auflag

  26.     Meyer, H., von Ohlen, T. , Panz, M. and Paululat, A. (2010) The disintegrin and metalloprotease Meltrin from Drosophila forms oligomers via its protein binding domain and is regulated by the homeobox protein VND during embryonic development. Insect Biochemistry and Molecular Biology 40 (11): 814-823

  27.     Tögel, M., Pass, G. and Paululat, A. (2010) Herzen beflügeln Fliegen. BioSpektrum 5: 516-519

  28.     Meyer, H., Panz, M., Zmojdzian, M., Jagla, K. and Paululat, A. (2009) Neprilysin 4, a novel endopeptidase from Drosophila melanogaster displays distinct substrate specificities and exceptional solubility states. Journal of Experimental Biology 212: 3673-3683.  

  29.     Sellin, J., Drechsler, M., Nguyen, H. and Paululat, A. (2009) Antagonistic function of Lmd and Zfh1 fine tunes cell fate decisions in the Twi and Tin positive mesoderm of Drosophila melanogaster. Developmental Biology 326: 444-455

  30.     Lehmacher, C., Tögel, M., Pass, G. and Paululat, A. (2009) The Drosophila wing hearts consist of syncytial muscle cells that resemble adult somatic muscles. Arthropod Structure & Development 38: 111-123

  31.     Hunnekuhl, V., Bergter, A., Purschke, G. and Paululat, A. (2009) Development and embryonic pattern of body wall musculature in the crassiclitellate Eisenia andrei (Annelida, Clitellata) Journal of Morphology 270: 1122-113

  32.    Tögel, M., Pass, G. and Paululat, A. (2008) The Drosophila wing hearts originate from pericardial cells and are essential for wing maturation. Developmental Biology 318: 29-37

  33.     Bergter, A., Brubacher, J. and Paululat, A. (2008) Muscle formation during embryogenesis of the polychaete Ophryotrocha diadema (Dorvilleidae) - new insights into annelid muscle patterns. Frontiers in Zoology 5: 1 (p. 1-18)

  34.     Johnson, A.N., Burnett, L.A., Sellin, J., Paululat, A., Newfeld, S.J. (2007) Defective Dpp signaling results in heart overgrowth and reduced cardiac output in Drosophila. Genetics 176:1609-1624

  35.     Bergter, A., Hunnekuhl, V., Schniederjans, M. and Paululat, A. (2007) Evolutionary aspects of pattern formation during clitellate muscle formation. Evolution & Development 9(6): 602-617

  36.     Popichenko, D., Sellin, J., Bartkuhn, M. and Paululat, A. (2007) Hand is a direct target of the forkhead transcription factor Biniou. BMC Developmental Biology 7: 49 (p. 1-9)

  37.     Bergter, A. and Paululat, A. (2007) Pattern of Body-wall Muscle Differentiation during Embryonic  Development of the Oligochaete Enchytraeus coronatus  (Annelida). Journal of Morphology 268: 537-549   

  38.     Albrecht, S., Wang, S., Holz, A., Bergter,  A. and Paululat, A. (2006) The ADAM metalloprotease Kuzbanian  is essential for heart formation in Drosophila melanogaster. Mechanisms of Development 123 (5): 372-387

  39.     Sellin, S., Albrecht, S., Kölsch, V.  and Paululat, A. (2006) Dynamics of heart differentiation,  visualized utilizing enhancer elements of the Drosophila  melanogaster bHLH transcription factor Hand. Gene Expression Patterns 6(4): 360-375

  40.     Popichenko, D. and Paululat, A. (2004) Cell fate decisions in the Drosophila dorsal vessel depend  on the multiadapter protein Inscuteable. Genesis 40: 218-222

  41.     Bergter,  A., Brand, C., Beck, L. and Paululat, A. (2004)The  embryonic development of the oligochaete Enchytraeus coronatus:  a SEM and histological study of embryogenesis from one-cell stage  to hatching. Journal of Morphology 261: 26-42

  42.     Brand, C., Bergter, A. and Paululat, A. (2003) Cloning of a twist orthologue from Enchytraeus coronatus (Annelida. Oligochaeta). DNA Sequence 14(1): 25-31

  43.     Kölsch, V. and Paululat, A. (2002) The highly conserved cardiogenic bHLH factor Hand is specifically expressed in circular viszeral muscle progenitor cells and in all cell types of the dorsal vessel during Drosophila embryogenesis. Dev. Genes & Evol. 212: 473-485

  44.     Lier, S. and Paululat, A. (2002) Characterization of the Drosophila proteasome regulatory particle subunit Rpn6 and its  interaction with signalosome subunit Alien/CSN2. Gene 298: 109-119

  45.     Rau, A., Buttgereit, D., Holz, A., Fetter, R., Doberstein, S.K., Paululat, A., Staudt, N., Skeath, J., Michelson, A.M. and Renkawitz-Pohl, R. (2001) During Drosophila muscle development rolling pebbles (rols) is required in muscle precursor cells to recruit further myoblasts for fusion. Development 128 (24) 5061-5073

  46.     Sievert, V., Kuhn, S., Paululat, A. and Traut, W. (2000) Sequence conservation and expression of the Sex-lethal homologue in the fly Megaselia scalaris. Genome 43 (2): 382-390

  47.     Grzeschik, N., Breuer, S., Renkawitz-Pohl, R. and Paululat, A. (1999) Molecular characterization of a point mutation in the Drosophila inscuteable gene. D.I.S.  82: 27-29

  48.     Paululat, A., Breuer, S. and Renkawitz-Pohl, R. (1999) Determination and development of the larval muscle pattern in Drosophila melanogaster. Cell & Tiss. Res. 296, 151-160

  49.     Dressel, U., Thormeyer, D., Altincicek, B., Paululat, A., Eggert, M., Schneider, S., Tenbaum, S. P., Renkawitz, R. and Baniahmad, A. (1999) Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily. Mol. Cell. Biol. 19, 3383-3394

  50.     Paululat, A., Holz, A. and Renkawitz-Pohl, R. (1999) Essential genes for myoblast fusion in Drosophila embryogenesis.  Mech. Dev. 83, 17-26

  51.     Hassan, B.A., Prokopenko, S.N., Breuer, S., Zhang, B., Paululat, A. and Bellen, H. (1998) skittles, a Drosophila phosphatidylinositol 4-phosphate 5-kinase, is required for cell viability, germline development and bristle formation, but not for neurotransmitter release. Genetics 150, 1527-1537

  52.     Knirr, S., Breuer, S., Paululat, A. and Renkawitz-Pohl, R. (1997) Somatic mesoderm differentiation, and the development of a subset of pericardial cells depend on the not enough muscle (nem) locus, which contains the inscuteable gene and the intron located gene skittles. Mech. Dev. 67, 69-81

  53.     Paululat, A., Goubeaud, A., Damm, C., Knirr, S., Burchard, S. and Renkawitz-Pohl, R. (1997) The mesodermal expression of rolling stone (rost) is essential for myoblast fusion in Drosophila and encodes a potential transmembrane protein. J. Cell Biol.138, 337-348

  54.     Goubeaud, A., Knirr, S., Renkawitz-Pohl, R. and Paululat, A. (1996) The Drosophila gene alien is expressed in the muscle attachment sites during embryogenesis and encodes a protein highly conserved between plants, Drosophila and vertebrates. Mech. Dev. 57, 59-68

  55.     Paululat, A. (1996) try29F (Drosophila trypsin-related protein), a new member of the Drosphila trypsin-like protease gene family, is specifically expressed in the posterior midgut. Gene 172, 245-247

  56.     Buttgereit, D., Paululat, A. and Renkawitz-Pohl, R. (1996) Muscle development and attachment to the epidermis is accompanied by expression of ß3 and ß1 tubulin isotypes, respectively. Int. J. Dev. Biol. 40, 189-196

  57.     Burchard, S., Paululat, A., Hinz, U. and Renkawitz-Pohl, R. (1995) The mutant not enough muscles (nem) reveals reduction of the Drosophila embryonic muscle pattern. J. Cell Sci. 108, 1443-1454

  58.     Paululat, A., Burchard, S. and Renkawitz-Pohl, R. (1995) Fusion from myoblasts to myotubes is dependent on the rolling stone gene (rost) of Drosophila. Development 121, 2611-2620.