Publications
Kelkenberg
M., Odman-Naresh J., Muthukrishnan S., Merzendorfer H. (2014) Chitin is a
necessary component to maintain the barrier function of the peritrophic matrix
in the insect midgut. Insect Biochem. Mol. Biol., in press.
Demaeght P., Osborne E.J., Odman-Naresh J., Grbić
M., Nauen R., Merzendorfer H., Clark R.M., Van
Leeuwen T. (2014) High resolution genetic mapping uncovers chitin synthase-1 as
the target-site of the structurally diverse mite growth inhibitors
clofentezine, hexythiazox and etoxazole in Tetranychus urticae. Insect Biochem. Mol. Biol. 51, 52-61.
Agrawal
S., Kelkenberg M., Begum K., Steinfeld L.,
Williams C. E., Kramer K.J., Beeman R.W., Park Y., Muthukrishnan S.,
Merzendorfer H. (2014) Two essential peritrophic matrix proteins mediate matrix
barrier functions in the insect midgut. Insect Biochem.
Mol. Biol. 49, 24-34.
Merzendorfer H. (2014) ABC Transporters and
their role in protecting insects from pesticides and their metabolites. In Target receptors in the control of insect
pests: Part II (Ed. Cohen, E.), first edition, pp. 1-73, Advances in Insect
Physiology 46, Elsevier, Oxford.
Odman-Naresh J., Duevel
M., Muthukrishnan S., Merzendorfer H. (2013) A lepidopteran-specific gene
family encoding valine-rich midgut proteins. PLoS One 8:e82015.
Broehan
G., Kroeger T., Lorenzen M., Merzendorfer H. (2013) Functional analysis of the
ATP-binding cassette (ABC) transporter gene family of Tribolium castaneum. BMC
Genomics 14:6.
Merzendorfer H. (2013) Insect-derived
chitinases. Adv. Biochem. Eng. Biotechnol. 136, 19-50.
Merzendorfer
H. (2013) The Integument. In The Insects – Structure
and Function (Eds. Douglas, A.E., Simpson, S.J.), fifth edition, pp. 463-498,
Cambridge University Press, Cambridge.
Merzendorfer
H., (2013) Chitin synthesis inhibitors: old molecules and new developments.
Insect Science 20, 121-138.
Merzendorfer
H., Heinisch J. (2013) Microcompartments within the yeast plasma membrane.
Biol. Chem. 394, 189-202.
Van
Leeuwen T., Demaeght P., Osborne E.J., Dermauw W., Gohlke S., Nauen R., Grbic M., Tirry L., Merzendorfer
H., Clark R.M. (2012). Population bulk segregant mapping uncovers resistance
mutations and the mode of action of a chitin synthesis inhibitor in arthropods.
Proc. Natl. Acad. Sci. USA 109, 4407-12.
Muthukrishnan
S., Merzendorfer H., Arakane Y., Kramer K. J. (2012) Chitin Metabolism in
Insects. In Comprehensive Molecular Insect Science (Gilbert,
L. I., Ed.), Elsevier Academic Press, San Diego, pp.193-235.
Merzendorfer
H., Kim, H. S., Chaudari S. S., Kumari,
M., Specht, C. A., Butcher, S., Brown, S. J., Manak, J. R., Beeman R.W. Kramer K.J., Muthukrishnan S.
(2012) Genomic and proteomic studies on the effects of the insect growth
regulator diflubenzuron in the model beetle species Tribolium castaneum. Insect Biochem. Mol. Biol. 42:264-276.
Merzendorfer
H. (2011) The cellular basis of chitin synthesis in
fungi and insects: common principles and differences. Eur. J. Cell Biol. 90, 759-769.
Blaesse A.K., Broehan G., Meyer
H., Merzendorfer H., Weihrauch D. (2010). Ammonia
uptake in Manduca sexta midgut is mediated by an amiloride
sensitive cation/proton exchanger: Transport studies
and mRNA expression analysis of NHE7, 9, NHE8, and V-ATPase (subunit D). Comp. Biochem. Physiol. A 157, 364-376.
Meissner, D., Odman-Naresh, J., Vogelpohl,
I., Merzendorfer, H. (2010). A novel role of the yeast CaaX protease Ste24 in chitin synthesis. Mol. Biol. Cell, 21, 2425-33.
Prasad
E.R., Merzendorfer H., Madhurarekha Ch., Dutta-Gupta
A., Padmasree K. (2010) Bowman-Birk
proteinase inhibitor from Cajanus Cajan
seeds: purification, characterization and insecticidal properties. J. Agric. Food Chem. 58, 2838-2847.
Broehan
G., Arakane Y, Beeman R.W., Kramer K.J., Muthukrishnan S. Merzendorfer, H.
(2010) Molecular analyses of chymotrypsin-like peptidases from Tribolium
castaneum involved in digestion and molting. Insect Biochem.
Mol. Biol. 40, 274-283.
Kaufmann
C., Merzendorfer H., Gäde G. (2009) The Adipokinetic
Hormone System in Culicinae (Diptera:
Culicidae): Molecular Identification and
Characterization of two Adipokinetic Hormone (AKH) Precursors from Aedes
aegypti and Culex pipiens
and two Putative AKH Receptor Variants from Aedes aegypti. Insect
Biochem. Mol. Biol. 39, 770-81.
Merzendorfer,
H. (2009) Chitin: structure, function and metabolism. In The sugar code:
fundamentals of glycosciences (Ed. H.-J. Gabius),
Wiley-VCH, Weinheim
Maue L., Meissner D., Merzendorfer H. (2009)
Purification of an active, oligomeric chitin synthase complex from the midgut
of the tobacco hornworm. Insect Biochem. Mol. Biol. 39,
654-659.
Arakane
Y., Begum K., Dixit R., Park Y., Specht C.A.,
Merzendorfer H., Kramer K.J., Muthukrishnan S., Beeman R.W. (2009) Analysis of
functions of the chitin deacetylase gene family in
Tribolium castaneum. Insect Biochem. Mol. Biol. 39,
355-365.
Broehan
G., Kemper M., Driemeier D., Vogelpohl I. and Merzendorfer H. (2008) Cloning
and expression analysis of midgut chymotrypsin-like proteinases in the tobacco
hornworm. J. Insect Physiol. 54, 1243-1252.
Broehan
G., Zimoch L., Wessels A., Ertas B. and Merzendorfer H. (2007) A
chymotrypsin-like serine protease interacts with the chitin synthase from the
midgut of the tobacco hornworm. J. Exp. Biol. 210, 3636-3643.
Merzendorfer,
H. (2006) Insect chitin synthases: a review. J. Comp. Physiol. B 176, 1-15.
Hogenkamp D.G., Arakane, Y. Zimoch L., Merzendorfer, H., Kramer K.J.,
Beeman, R.W., Kanost, M.R., Specht,
C.A., Muthukrishnan, S. (2005) Chitin synthase genes in Manduca sexta:
Characterization of a gut-specific transcript and differential tissue
expression of alternately spliced mRNAs during development. Insect
Biochem. Mol. Biol. 35, 529-540
Zimoch L, Hogenkamp
D.G., Kramer, K. Muthukrishnan K., Merzendorfer, H. (2005) Regulation of chitin
synthesis in the larval midgut of Manduca sexta. Insect Biochem. Mol.
Biol. 35, 515-527
Vitavska
O, Merzendorfer H, Wieczorek H. (2005) The V-ATPase subunit C binds to polymeric
F-actin as well as to monomeric G-actin and induces cross-linking of actin
filaments. J Biol. Chem. 280, 1070-1076
Merzendorfer
H., Zimoch L. (2003) Chitin metabolism in insects: structure, function and
regulation of chitin synthases and chitinases. J. Exp. Biol. 206, 4393-4412
Wieczorek
H., Huss M., Merzendorfer H., Reineke S., Vitavska
O., Zeiske W. (2003) The
Insect Plasma Membrane H+ V-ATPase: Intra-, Inter-, and Supramolecular
Aspects. J. Bioenerg. Biomembr. 35, 359-366
Vitavska
O, Wieczorek H, Merzendorfer H. (2003) A novel role for subunit C in mediating
binding of the H+-V-ATPase to the actin cytoskeleton. J. Biol. Chem. 278,
18499-18505
Zimoch L. und Merzendorfer H. (2002) Immunolocalization of chitin synthase in the tobacco
hornworm. Cell Tissue Res. 308, 287-297
Reineke S., Wieczorek H., Merzendorfer H. (2002) Expression of Manduca
sexta V-ATPase genes mvB, mvG
and mvd is regulated by ecdysteroids. J. Exp. Biol.
205, 1059-1067
Merzendorfer
H., Reineke S., Zhao X. F., Jacobmeier
B., Harvey W. R., Wieczorek H. (2000) The multigene family of the tobacco
hornworm V-ATPase: novel subunits a, C, D, H, and putative isoforms. Biochim. Biophys. Acta.
1467, 369-379
Wieczorek
H., Grüber G., Harvey W. R., Huss M., Merzendorfer H,
Zeiske W. (2000) Structure and regulation of insect
plasma membrane H(+)V-ATPase. J. Exp. Biol. 203,
127-135
Merzendorfer
H., Huss M., Schmid R., Harvey W. R., Wieczorek H.
(1999) A novel insect V-ATPase subunit M9.7 is glycosylated extensively. J.
Biol. Chem. 274, 17372-17378
Wieczorek
H., Grüber G., Harvey W. R., Huss M., Merzendorfer H.
(1999) The plasma membrane H+-V-ATPase from tobacco
hornworm midgut. J. Bioenerg. Biomembr. 31, 67-74
Merzendorfer
H., Harvey W. R., Wieczorek H. (1997) Sense and antisense RNA for the membrane
associated 40 kDa subunit M40 of the insect V-ATPase. FEBS Lett.
411, 239-244.
Merzendorfer H., Gräf R., Huss M., Harvey W.
R., Wieczorek H. (1997) Regulation of proton-translocating V-ATPases. J. Exp. Biol. 200, 225-235
Lepier A., Gräf R., Azuma M., Merzendorfer H., Harvey W. R., Wieczorek
H. (1996) The peripheral complex of the tobacco hornworm V-ATPase contains a
novel 13-kDa subunit G. J. Biol. Chem. 271, 8502-8508.
News & Views Article
Merzendorfer
H. (2014) Anthropogenic pollutants disturb moth navigation. J. Exp. Biol. 217
(21), in press.
Merzendorfer H. (2014) A novel ant protein for
chemical communication. J.
Exp. Biol. 217 (15), 2624-2625.
Merzendorfer H. (2014) A unique way to see
colors. J. Exp. Biol. 217
(9), 1422.
Merzendorfer H. (2014) Airway clearance by
reducing tensile strength. J.
Exp. Biol. 217 (3), 315-316.
Merzendorfer
H. (2013) A new clock for molting. J. Exp. Biol. 216
(21), vi.
Merzendorfer
H. (2013) Cell death triggers life in muscles. J. Exp. Biol.
216 (15), v-vi.
Merzendorfer
H. (2013) Protecting sperm in seminal fluid. J. Exp. Biol.
216 (9), v.
Merzendorfer H. (2013) A new view of
photoreceptors. J. Exp. Biol. 216 (3), iv.
Merzendorfer
H. (2012) Striated muscles evolved independently. J. Exp. Biol. 215 (21), iv.
Merzendorfer
H. (2012) Hydrophobicity counts in large amounts. J. Exp.
Biol. 215 (15), v.
Merzendorfer H. (2012) A potential antidote to
a myotoxin from snake venomes. J.
Exp. Biol. 215 (9), iv.
Merzendorfer H (2012) Insects’ intestinal
barrier against infection. J.
Exp. Biol. 215 (3), iv.
Merzendorfer H (2011) Parasites’ grappling
hook for host cell boarding. J.
Exp. Biol. 214(21), v-vi
Merzendorfer
H (2011) Active component in honeybees’ royal jelly discovered. J. Exp. Biol.
214(15), iv
Merzendorfer
H (2011) Mechanism for stretch activation proposed. J. Exp. Biol. 214(9), iv-v
Merzendorfer H (2011) Immune memory found in
mosquitoes. J. Exp. Biol. 214 (3), iv-a
Merzendorfer
H (2010) Pri peptides switch on transcription factor.
J. Exp. Biol. 213(21), v
Merzendorfer
H. (2010). A taste for water. J.
Exp. Biol., 213(15), v-vi.
Merzendorfer
H. (2010). Eat less, live longer. J. Exp. Biol.,
213 (9), vi
Merzendorfer H. (2010). A mitochondrial door for calcium. J. Exp. Biol., 213 (4), v-a
Merzendorfer
H. (2009). Epithelial polarity: a complex picture. J. Exp. Biol., 212 (23), vi
Merzendorfer
H. (2009) GnRH evolutionarily conserved in
reproduction. J. Exp. Biol., 212 (17), vi
Merzendorfer H. (2009) Bridging the nephrocyte gap. J.
Exp. Biol. 212 (12), iv
Merzendorfer
H. (2009) Beetle’s moult is different from fly’s. J. Exp. Biol. 212 (5), vi
Merzendorfer
H. (2008) Sleepless gene helps flies 40 winks. J. Exp. Biol. 211 (21), vi
Merzendorfer
H. (2008) Follow the nose. J. Exp. Biol. 211 (15), iv
Merzendorfer
H. (2008) Subtle differences. J. Exp. Biol. 211 (9),
v-a
Merzendorfer H. (2008) Size matters. J. Exp. Biol. 211 (3), vii
Merzendorfer H. (2007) Timeless clock. J. Exp. Biol. 210 (21), vii
Merzendorfer H. (2007) Cilia’s coxswain. J. Exp. Biol. 210 (15), v
Merzendorfer H. (2007) A hot venom. J. Exp. Biol. 210 (7), v-v
Merzendorfer
H. (2007) Exploiting erythrocytes. J. Exp. Biol. 210 (1), v-vi
Merzendorfer
H. (2006) Disc control. J. Exp. Biol. 209 (19), vii
Merzendorfer
H. (2006) Soluble oligomer triggers memory loss. J.
Exp. Biol. 209 (13), v
Merzendorfer
H. (2006) Clip it. J. Exp. Biol. 209 (7), vii
Merzendorfer H. (2006) Old pore – new edition. J. Exp. Biol. 209 (1), iii
Merzendorfer H. (2005) Modular functions. J. Exp. Biol. 208 (19), iv
Merzendorfer H. (2005) A sexy receptor. J. Exp. Biol. 208 (13), iv.
Merzendorfer
H. (2005) microRNA hit it macro. J. Exp. Biol. 208 (17), iv.
Merzendorfer
H. (2005) Muscular Dystrophies: A novel player. J. Exp. Biol. 208 (1), vii
Merzendorfer
H. (2004) Calcium pump: a closer look. J. Exp. Biol.
207 (21), vii
Merzendorfer H. (2004) A bulk of bundles. J. Exp. Biol. 207 (15), vii
Merzendorfer
H. (2004) Cover the distance. J. Exp. Biol. 207 (9), vii
Merzendorfer H. (2004) Sensor not transporter. J.
Exp. Biol. 207 (3), vii.
Merzendorfer
H. (2003) Flip and fuse. J. Exp. Biol. 206 (22), 3892
Merzendorfer
H. (2003) Sniffing sperm. J. Exp. Biol. 206 (15), 2528
Merzendorfer
H. (2003) Killing Drosophila with ineffective toxins. J. Exp. Biol. 206 (9), 1433a-1434a
Merzendorfer H. (2003) Puzzling contractile
rings. J. Exp.
Biol. 206, 428